By analyzing the configurations of nucleoprotein complexes using gelFRET analysis (Leonard, 1998),
we found that ATF2-Jun heterodimers bind in both orientations to the
interferon-beta enhancer in association with IRF3 and HMGI (Burns, 2012). | By visualizing multiprotein complex binding on
polytene chromosomes using BiFC analysis, we found that the dKeap1-CncC
xenobiotic response complex binds and regulates developmental genes and controls Drosophila metamorphosis (Deng, 2014). | By mapping the genome-wide locations of KAP1 and Ring1b binding in ES cells, we found that both KAP1 and Ring1b bind and regulate a large proportion of the genes that are induced or repressed during embryonic stem cell differentiation (Cheng, 2014). |
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